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阿托伐他汀和血塞通胶囊对脑梗死患者颈动脉粥样硬化斑块稳定性的临床干预研究(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2010年04期
页码:
25-0
栏目:
临床研究
出版日期:
2010-08-17

文章信息/Info

Title:
The Clinic Research of Atorvastatin and Notoginseng Triterpenes Treating CerebralInfarction Patient With Carotid Atherosclerosis Dollop
作者:
张永全1褚斐2陆晖1谭文澜2
(1.广西中医学院附属瑞康医院,广西南宁530011;2.北京朝阳区高碑店社区卫生服务中心,北京100124)
Author(s):
ZHANG Yong-quan1CHU Fei2LU Hui1TAN Wen-lan1
(1.Ruikang Hospital of GuangXi University TCM,Nanning Guangxi 530011;2.Beijing Gaobeidian Community Health Services Center,Beijing 100124)
关键词:
颈动脉粥样硬化斑块稳定性阿托伐他汀血塞通软胶囊
Keywords:
atherosclerosis dollopstabilityatorvastatinsanqizongzaodai
分类号:
R278
DOI:
-
文献标识码:
A
摘要:
目的:观察阿托伐他汀和血塞通胶囊对脑梗死患者颈动脉粥样硬化斑块稳定性,血脂水平影响的临床疗效。方法:颈动脉粥样硬化斑块患者120例,分西药组和中西药组各60例。两组均给予阿托伐他汀片,中西药组再给予血塞通胶囊,疗程为6个月。结果:①西药组和中西药组中的血脂(TC、TG、LDL-C)均显著降低(P<005);②不稳定斑块组颈动脉IMT、斑块积分有明显下降,有统计学意义(P<005);稳定斑块组未见到明显变化(P>005)。结论:阿托伐他汀片可降低不稳定斑块颈动脉内膜中层厚度(IMT),降低颈动脉斑块积分;阿托伐他汀片和血塞通软胶囊临床结合使用效果更加明显。
Abstract:
Objective:To observe the clinic effect of atorvastatin and notoginseng triterpenes on carotid atherosclerosis dollop stability and blood grease.Methods:Choose 120 patients with carotid atherosclerosis dollop.Then divide 120 patients accord to different conditions into two groups,Traditional medicine group(TMG)and Western medicine group (WMG).Two groups administer Atorvastatin tablets.At the same time TMG administer xuesaitong capsule once more.The course of treatment was 6 months.Results:A.WMG and TMG have evident drop in TC,TG,LDL-C(P<005).B.Instability dollop group have evident drop in carotid IMT,dollop integral, showing statistics difference(P<005).Stability dollop group have no evident changes,showing no statistics difference(P>005).Conclusion:Atorvastatin patch can reduce instability dollop carotid IMT and dollop integral,thereby reduce cerebral incidence of disease and death rate.Atorvastatin tablets and notoginseng triterpenes used together have better clinic effect.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期:2010—03—16修回日期:2010—05—19作者简介:张永全(1965-),男,广西南宁人,副教授,硕士生导师,主要研究方向:神经系统疾病的中西医结合研究。
更新日期/Last Update: 2010-08-01