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栽培滇龙胆的化学成分研究(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2010年05期
页码:
8-12
栏目:
方药研究
出版日期:
2010-10-17

文章信息/Info

Title:
Chemical Constituents of Cultivated Gentiana Rigescens Franch.Based on Latent Endogenous Toxicity Theory
作者:
朱卫萍1赵磊1张国华1饶高雄12
1.云南中医学院中药学院,云南昆明650500;2.云南省农业科学院药用植物研究所,云南昆明650231
Author(s):
ZHU Wei-Ping1ZHAO Lei1ZHANG Guo-hua1 RAO Gao-Xiong1 2*
1.College of Pharmacy,Yunnan university of TCM,Kunming Yunnan 650500,China;2.Institute of Medicinal Plant,Yunnan Academy of Agriculture Science,Kunming Yunnan 650231,China
关键词:
滇龙胆栽培化学成分含量测定品质评价
Keywords:
Gentiana rigescens FranchPlanting Chemical constituentsQualities appraisement
分类号:
R284
DOI:
-
文献标识码:
A
摘要:
目的:研究栽培滇龙胆(Gentiana rigescens Franch.)的化学成分,比较栽培品和野生品化学成分的异同,评价栽培滇龙胆药材品质。方法:用色谱法分离化学成分,根据波谱分析鉴定化学结构;用薄层色谱(TLC)和高效液相色谱(HPLC)进行化学成分的比较分析。结果:从栽培滇龙胆药材中分离鉴定了19个成分;栽培品的TLC及HPLC谱图和野生品一致,龙胆苦苷的含量分别为431%(栽培品)和471%(野生品)。结论:首次研究了栽培滇龙胆的化学成分,并明确其所含化学成分类型、主要有效成分和野生滇龙胆一致;滇龙胆栽培品和野生品中龙胆苦苷含量相当且均高于法定标准;滇龙胆人工栽培是成功的,应大力发展规模种植。
Abstract:
Objective:To study chemical constituents of cultivated Gentiana rigescen and to appraise the qualities of cultivated species by means of comparison on chemical substance with that of the wild species. Method:The chemical constituents were isolated by chromatography and their structures were identified by spectroscopic analysis. The comparison on chemical substance of cultivated and wild Gentiana rigescens was carried out with TLC and HPLC analysis. Results:Nineteen compounds,including main component gentiopicroside,were isolated and identified from the cultivated Gentiana rigescens. The chromatogram of TLC and HLPC analysis of cultivated Gentiana rigescens showed almost same spots or peaks as those of wild species. Their contents of gentiopicroside were 471%(wild species)and 432%(cultivated species),respectively. Conclusion:The chemical constituents of cultivated Gentiana rigescens was reported for the first time. The cultivated Gentiana rigescens was identical in chemical character with the wild species, and the contents of principal bioactive compound gentiopicroside in both of cultivated and wild species were more than the legal standard in China Pharmacopoeia. Planting of Gentiana rigescens was successful and this agricultural technology should be extended.

参考文献/References

[1]国家药典委员会.中华人民共和国药典[S].一部.北京:化学工业出版社,2005:64-65.
[2]云南省药物研究所.云南重要天然药物[M].昆明:云南科技出版社,2006:343-353.
[3]李智敏,赵磊,白艳婷,等.不同产地滇龙胆中龙胆苦苷的含量测定[J].云南中医学院学报,2008,31(6):10-12.
[4] 赵磊,李智敏,白艳婷,等.滇龙胆地上部分的化学成分研究[J].云南中医学院学报,2009,32(2):27-31.
[5]王世盛,徐青,肖红斌,等.抱茎獐牙菜中的苷类成分[J].中草药,2004,38(5):847-849.
[6]罗跃华,聂瑞麟.狭叶獐牙菜中的两个环烯醚单萜苷[J].药学学报,1992,27(2):125-129.
[7]Tan Rong-Xiang,Wolfender J L,Ma Wei-Guang.Secoiridoides and antifungal aromatic acids from Gentiana algida[J].Phytochemistry,1996,41(1):111-116.
[8]王明安,王明奎,彭树林,等.青檀树皮中的化学成分[J].天然产物研究与开发,2001,13(6):5-8.
[9]秦文杰,王钢力,林瑞超.短柱肖菝葜化学成分的研究(Ⅱ)[J].中草药,2007,38(10):1466-1468.
[10]叶婕颖,张庆芝,饶高雄.傣药芽鲁哈咪卖的化学成分研究[J].中草药,2009,40(6):850-852.
[11]薛慧清,杨红澎,汪汉卿,等.黄毛橐吾三萜类成分研究[J].中国中药杂志,2008,33(3):272-275.
[12]田军,吴凤锷,邱明华,等.匙叶翼首花的化学成分[J].天然产物研究与开发,2000,12(1):35-37.
[13]孙南君,夏春芳.坚龙胆中化学成分的研究[J].中药通报,1984,9(1):33-34.
[14]张建生,田子新,楼之岑,等.九种龙胆中五种裂环环烯醚萜甙类苦味成分的高效液相色谱定量分析[J].药学学报,1991,26(11):864-870.
[15]许敏,王东,张颖君,等.坚龙胆中的一个新裂环烯醚萜苷[J].云南植物研究,2006,28(6):669-672.
[16]Xu M,Wang D,Zhang YJ,et aL.Dammarane Triterpenoids from the Roots of Gentiana rigescens[J].J Nat Prod.2007,70(5):880-883.
[17]李文龙,陈军辉,殷月芬,等.龙胆药材中龙胆苦苷和马钱子苷酸含量的测定及其指纹图谱研究[J].药学学报,2007,42(5):566-570.

备注/Memo

备注/Memo:
基金项目:云南省发改委产业关键技术开发专项“滇龙胆的人工驯化及规范化种植关键技术研究与示范”。收稿日期:2010—04—20修回日期:2010—07—22作者简介:朱卫萍(1984),女,云南镇源人,云南中医学院硕士研究生,主要从事中药化学成分分析研究工作。△通讯作者:饶高雄,Tel:0871-5919558;Email:rao13987124569@qqcom
更新日期/Last Update: 2010-10-17