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急性脑梗死患者血清TNF-a和IL-6的表达及疏血通干预的临床意义(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2013年02期
页码:
70-0
栏目:
临床研究
出版日期:
2013-04-20

文章信息/Info

Title:
Expression of TNF-a and IL-6 in Patients with Acute Cerebral Infarction after Clinical intervention of Shuxuetong Injection and Clinical Significance
作者:
王咏龙邹晓辉党利华
广东省深圳市第八人民医院,广东深圳 518000
Author(s):
WANG Yong-long ZOU Xiao-hui DANG Li-hua
Shenzhen Eighth People’s Hospital,Shenzhen Guangdong 518000
关键词:
急性脑梗塞 疏血通 TNF-a IL-6
Keywords:
acute cerebral infarctionShuxuetong injectionTNF-aIL-6
分类号:
R255.2
DOI:
-
文献标识码:
A
摘要:
目的研究急性脑梗塞患者血清肿瘤坏死因子(TNF-a)和血清白介素6(IL-6)水平及疏血通干预后的变化,探讨其神经保护机制和临床意义。方法用临床随机对照的观察方法,将56例急性脑梗死患者按随机数字表法将入院的急性脑梗死患者随机分为疏血通治疗者和灯盏细辛对照组。两组疗程均为14d。分别在治疗1d、3d、7d和14d检测血清TNF-a和IL-6含量。结果疏血通治疗组治疗后患者血清TNF-a和IL-6含量明显减少,与灯盏细辛对照组比较差异有显著性(P<0.05)。结论疏血通能减少血清TNF-a和IL-6含量含量来改善急性脑梗塞患者缺损的神经功能。
Abstract:
Objective To observe influence of Shuxuetong injection on serum Tumor necrosis factor(TNF-a)and Interleukin 6(IL-6)in patients with acute cerebral infarction and explore its neurological protective mechanisms and clinical significance. Methods with clinical randomized controlled observation method,56 cases were randomly divided into Shuxuetong injection treatment group and the control group of Erigeron breviscapus,28cases in each group. The period of treatment of two groups was 14 days. On 1d,3d,7d and 14d of reatment,serum TNF-a and IL-6 levels were detected. Results Compared with the control group,serum TNF-a and IL-6 were significantly decreased after treatment of 3d,7d and 14d and there were significant differences(P<0. 05). Conclusion Shuxuetong injection can decrease TNF-a and IL-6 level of treatment group patients to improve neural function defect of acute cerebral infarction patients.

参考文献/References

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备注/Memo

备注/Memo:
收稿日期: 2012 - 11 - 19修回日期: 2013 - 04 - 02 作者简介: 王咏龙(1974~),男,汉族,湖南岳阳人,主治医师,博士研究生,研究方向:脑血管疾病
更新日期/Last Update: 2013-05-20