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中西医结合治疗糖尿病周围神经病变临床疗效观察(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2013年02期
页码:
76-0
栏目:
临床观察
出版日期:
2013-04-20

文章信息/Info

Title:
Clinical Effect Observation of Integrated Traditional Chinese and Western Medicine in Treatment of Patients with Diabetic Peripheral Neuropathy
作者:
邓红玲张金红
恩施州中心医院,湖北恩施 445000
Author(s):
DENG Hong-ling ZHANG Jin-hong
The Central Hospital of Enshi Prefecture, Enshi Hubei 445000,China
关键词:
糖尿病周围神经病变 益气活血方 甲钴胺 中西医结合
Keywords:
diabetic peripheral neuropathyPrescription for nourishing Qi and activating BloodMecobalaminintegrated traditional chinese and western medicine
分类号:
R255.4
DOI:
-
文献标识码:
A
摘要:
目的探讨中西医结合治疗糖尿病周围神经病变(DPN)的临床疗效。方法将78例确诊为DPN的患者随机分组为对照组和治疗组,2组患者均首先使用降糖药控制血糖在正常范围内。其中,对照组38例采用甲钴胺进行治疗,治疗组40例在甲钴胺治疗的基础上加用益气活血方进行治疗。15d为1个疗程,治疗2个疗程。在治疗过程中,观察正中神经和腓总神经的运动神经传导速度(MNCV)和感觉神经传导速度(SNCV)指标的变化情况。结果两组患者治疗2个疗程后,治疗组总有效率90.00%,对照组总有效率71.05%,两组总有效率比较差异有统计学意义(P<0.05),治疗组疗效优于对照组。两组患者治疗后正中神经和腓总神经的MNCV和SNCV均高于治疗前,治疗前后比较差异有统计学意义(P<0.05),且治疗组提高更为明显,治疗效果优于对照组,组间比较差异有统计学意义(P<0.05)。在治疗的过程中,对照组和治疗组并未出现严重的不良反应,未见明显的肝、肾功能损害,治疗前后比较差异无统计学意义(P>0.05)。结论中西医结合治疗DPN疗效可靠、安全性高,值得临床推广应用。
Abstract:
Objective To observe the clinical effect of integrated traditional chinese and western medicine in treatment of patients with diabetic peripheral neuropathy(DPN). Methods 78 patients with DPN were randomly divided into two groups. All patients were treated with hypoglycemic drugs to control blood sugar within the normal range first. 38 patients were allocated into control group treated with mecobalamin,while 40 patients were allocated into treatment group treated with Prescription for nourishing Qi and activating Blood combined with mecobalamin. Fifteen days is a course of treatment,and both groups were treated for two courses of treatment. In the treatment process,the motor nerve conduction velocity(MNCV)and sensory nerve conduction velocity(SNCV)of median and common peroneal nerve have been observed. Results After two courses of treatment,the total effective rate of treatment group is 90. 00%,and the total effective rate of control group is 71. 05%. By chi-square(χ2)test,there is significant difference in total effective rate compared the control group with the treatment group(P<0. 05),and compared with control group,treatment group has batter clinical effect. The MNCV and SNCV of median and common peroneal nerve are increasing more significantly in both control group and treatment group after treatment,compared with pre-treatment(P<0. 05),and compared with control group,treatment group has batter clinical effect(P<0. 05). In the treament of control group and treatment group,serious adverse reactions and significant liver and kidney dysfunction did not appear,compared with pre-treatment(P>0. 05). Conclusion There is significant clinical effect of integrated traditional chinese and western medicine in treatment of patients with diabetic peripheral neuropathy,and the treatment protocols is more secure which is worthy of clinical popularization and application.

参考文献/References

[1] 钟锦均. 参芎葡萄糖注射液治疗糖尿病周围神经病变的疗效观察[J]. 现代中西医结合杂志,2011,20(29):3681-3682.
[2] 卫坚,刘雪,张燕. 中西医结合治疗疼痛性糖尿病周围神经病变34例[J]. 云南中医学院学报,2007,30(5):48-49.
[3] 陆再英,终南山. 内科学[M]. 7版. 北京:人民卫生出版社,2008:770-793.
[4] 中华人民共和国卫生部. 中药新药临床研究指导原则:第1辑[S]. 1993:215-217.
[5] 衡先培. 糖尿病性神经病变诊断与治疗[M]. 北京:人民卫生出版社,2002:10.
[6] 吕仁和. 糖尿病及其并发症中西结合诊治学[M]. 北京:人民卫生出版社,1997:27.
[7] Little A A,Edwards J L,Feldman E L. Diabetic neuropathies[J]. Pract Neurol. 2007,7(2):82-92.
[8] 崔丽英. 糖尿病周围神经病的研究进展[J]. 中华神经科杂志,2006,39(7):433-435.
[9] 李鸾,刘伟. 糖尿病周围神经病变的中医药治疗进展[J]. 中国中医药现代远程教育,2011,9(15):156-157.
[10] 吴振丽. 舒血宁联合弥可保治疗糖尿病周围神经病变疗效观察[J]. 实用糖尿病杂志,2004,12(5):25.
[11] 朱燕. 自拟降糖通脉汤治疗糖尿病足早期30例[J]. 云南中医学院学报,2011,34(4):51-52.

备注/Memo

备注/Memo:
收稿日期: 2012 - 07 - 13修回日期: 2012 - 09 - 05 作者简介: 邓红玲(1962~),女,湖北恩施人,主任医师,从事糖尿病及其并发症的研究。
更新日期/Last Update: 2013-05-20