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山楂降脂丸联合小剂量辛伐他汀胶囊对脑梗死合并高脂血症的干预分析(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2013年04期
页码:
52-54
栏目:
临床研究
出版日期:
2013-08-25

文章信息/Info

Title:
Analysis of Hawthorn Jiangzhi Pill Combined with Small Dose of Simvastatin Capsules Combined Hyperlipidemia on Cerebral Infarction Intervention
作者:
王继华王素丽孔令风孟雪莲李建中赵军旗
河北省玉田县中医医院,河北玉田 064100
Author(s):
WANG Ji-hua WANG Su-li KONG Ling-feng MENG Xue-lian LI Jian-zhong ZHAO Jun-qi
Hebei Province Yutian County Hospital of TCM, Yutian Hebei 064100, China
关键词:
山楂降脂丸脑梗死高脂血症辛伐他汀
Keywords:
Hawthorn Jiangzhi pillcerebral infarctionhyperlipemiaSimvastatin
分类号:
R255.2
DOI:
-
文献标识码:
A
摘要:
目的观察山楂降脂丸联合辛伐他汀胶囊治疗脑梗死合并高脂血症的临床疗效。方法将86例脑梗死合并高血脂症患者随机分为2组。对照组41例,在抗血小板聚集、调整血压、控制血糖等常规治疗基础上,口服辛伐他汀胶囊;治疗组45例,在上述常规治疗基础上,口服小剂量辛伐他汀胶囊并口服山楂降脂丸。结果总有效率治疗组91.1%,对照组为75.6%,两组比较差异有显著性意义。治疗组、对照组治疗后总胆固醇、甘油三酯、高密度脂蛋白、低密度脂蛋白等指标均显著降低,差异有非常显著性意义;治疗组各项指标与对照组治疗后比较,差异有显著性意义。结论山楂降脂丸联合小剂量辛伐他汀胶囊能够明显降低血脂水平,促进脑梗死患者神经功能恢复,且无肝损害,便于长期服用,疗效优于辛伐他汀胶囊。
Abstract:
Objective To observe the clinical effect of Hawthorn Jiangzhi pill combined with simvastatin capsules in treatment of cerebral infarction in patients with hyperlipidemia. Methods 86 cases complicated with cerebral infarction patients with hyperlipidemia were randomly divided into 2 groups. 41 cases of the control group, the platelet aggregation,adjusting blood pressure,control blood glucose on the basis of conventional therapy, oral administration of simvastatin capsules(20mg,once daily); 45 cases in treatment group, on the basis of routine therapy, oral administration of small doses of simvastatin capsules(10mg, once daily) and oral Hawthorn Jiangzhi pill 6G,treatment 2 times a day. Results The total effective rate was 91.1% in treatment group, 75.6% in control group,there were significant differences between the two groups(P<0.01). The treatment group, the control of total cholesterol, triglyceride, high density lipoprotein, low density lipoprotein index group after treatment were significantly decreased,the difference was significant(P<0.05), the index of the treatment group and control group after treatment, the difference was significant(*P<0.05). Conclusion Hawthorn Jiangzhi pill combined with small dose of simvastatin capsules(10mg, once daily)can significantly reduce blood lipid level, promote the recovery of neurological function in patients with cerebral infarction, and without liver damage, convenient for long-term use, curative effect is better than that of simvastatin capsules(20mg, once daily).

参考文献/References

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备注/Memo

备注/Memo:
收稿日期: 2013 - 07 - 01修回日期: 2013 - 07 - 24 作者简介: 王继华(1971~),女,河北玉田人,副主任医师,从事神经内科、脑血管病的临床治疗和预防工作。
更新日期/Last Update: 2013-08-30