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儿童频复发型系膜增生性肾小球肾炎血脂水平与中医分型相关性分析(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2014年05期
页码:
73-76
栏目:
临床研究
出版日期:
2014-10-25

文章信息/Info

Title:
Analysis of the Relationship between Syndrome Pattern of Chinese Medicine and the Levels of Serum Lipoprotein of Frequent Relase Mesangial Proliferative Glomerulonephritis
作者:
张沛彭洪军任献国
南京军区南京总医院,江苏南京210003
Author(s):
ZHANG Pei PENG Hong-jun REN Xian-guo
Nanjing General Hospital of Nanjing Military Command, Nanjing 210003, China
关键词:
MsPGN频复发血脂中医证型儿童
Keywords:
MsPGN frequent relase serum lipoprotein syndrome pattern of Chinese medicine children
分类号:
R272
DOI:
-
文献标识码:
A
摘要:
目的探讨频复发型系膜增生性肾小球肾炎血脂水平与中医分型的关系。方法检查确 诊为频复发型系膜增生性肾小球肾炎患儿血脂水平及蛋白定量、尿NAG酶指标,并对该组患儿 进行中医分型,分析中医证型与血脂、蛋白定量、尿NAG酶水平之间关系。结果脾肾阳虚组和 肝肾阴虚组TC比肺脾气虚型高(P<0.05);脾虚湿困型组TG比肺脾气虚型高(P<0.05);脾肾 阳虚组和肝肾阴虚组LDL-C比肺脾气虚组高(P<0.01);脾肾阳虚组apoAI比肺脾气虚组高 (P<0.01);脾肾阳虚组和脾虚湿困组尿蛋白定量比肺脾气虚组高(P<0.01);脾肾阳虚组和 脾虚湿困组NAG酶比肺脾气虚组高(P<0.01)。结论血脂变化与儿童MsPGN的复发密切相关, 而根据中医的宏观辨证结合肾穿刺活检术,分析不同病理变化中医证型与血脂变化的关系,有 利于及时对此类疾病的诊断、治疗进行中医干预。
Abstract:
Objective It is to approach the relationship between syndrome pattern of Chinese medicine and the levels of serum lipoprotein of frequent relase mesangial proliferative glomerulonephritis. Methods Detect the levels of serum lipoprotein、urine protein、urine NAG enzyme of frequent relase mesangial proliferative glomerulonephritis of child patient, analyse the relationship between the levels of serum lipoprotein、urine protein、urine NAG enzyme and syndrome pattern of Chinese medicine. Results The levels of TC of asdthenic splenonephro Yang group and hepatic and renal Yin deficiency group was higher than Gasthenia of pulmonosplenic Qi group(P<0.05); the levels of TG of splenasthenic fluid-retention group was higher than Gasthenia of pulmonosplenic Qi group(P<0.05 ); the levels of LDL-C of asdthenic splenonephro Yang group and hepatic and renal Yin deficiency group was higher than Gasthenia of pulmonosplenic Qi group (P<0.01); the levels of apoAI of asdthenic splenonephro Yang group and was higher than Gasthenia of pulmonosplenic Qi group(P<0.01); the levels of urine protein of asdthenic splenonephro Yang group and splenasthenic fluid-retention group was higher than Gasthenia of pulmonosplenic Qi group(P<0.01); the levels of urine NAG enzyme of asdthenic splenonephro Yang group and splenasthenic fluid- retention group was higher than Gasthenia of pulmonosplenic Qi group(P<0.01). Conclusion There was close relation between the change of serum lipoprotein and recurrence of children with frequent relase MsPGN, According to the Chinese medicine macro discriminate and renal needle biopsy, to analyzing the relationship between pathological changes of syndrome pattern of Chinese medicine and change of serum lipoprotein, could make for the intervention of traditional Chinese medicine for the diagnosis and treatment of the disease in time.

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备注/Memo

备注/Memo:
收稿日期:2014-04-13 作者简介:张沛(1984-),男,河南汝州人,医学硕士,住院医师,从事小儿肾脏病临床 研究,E-mail:zhangpei.2008@hotmail.com
更新日期/Last Update: 2014-10-20