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|本期目录/Table of Contents|

头痛新1号治疗慢性偏头痛的临床研究(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2014年06期
页码:
36-38,55
栏目:
临床研究
出版日期:
2014-12-25

文章信息/Info

Title:
Clinical Study of ToutongXinNO. 1 in Treating Patients with Chronic Migraine Headaches
作者:
姜婷婷1李慧2白方会1伍志勇1聂玲辉1陈宝田1
1. 南方医科大学南方医院中医科,广东广州 510515;2. 广州市红十字会医院中医科,广东广州 510515
Author(s):
JIANG Ting-ting1 LI Hui2 BAI Fang-hui1 WU Zhi-yong1 NIE Ling-hui1 CHEN Bao-tian1
1. Department of Traditional Chinese Medicine, Nanfang Hospital Affiliated to Southern Medical University, Guangzhou 510515, China; 2. Department of Traditional Chinese Medicine, Guangzhou Red Cross Hospital, Guangzhou 510515, China
关键词:
头痛新1号 慢性偏头痛 盐酸氟桂利嗪
Keywords:
ToutongXinNO. 1 chronic migraine FlunarizineHydrochloride capsules
分类号:
R255
DOI:
-
文献标识码:
A
摘要:
目的探讨头痛新1号治疗慢性偏头痛的临床疗效。方法将80例慢性偏头痛患者随机分为治疗组和对照组,采用焦虑自评量表(SAS)及抑郁自评量表(SDS)评价其焦虑和抑郁程度。治疗组予头痛新1号,对照组予盐酸氟桂利嗪,2组疗程均为12周,治疗后比较各组间差异。结果2组治疗前后头痛程度、发作频率及持续时间比较均有显著差异(P<0.001);治疗组、对照组临床总有效率分别为95%,70%,组间比较有差异(P<0.05);服药12周后治疗组SDS和SAS评分明显降低(P<0.001),对照组差异不明显(P>0.001)。结论头痛新1号治疗慢性偏头痛疗效显著,能有效改善头痛患者伴随的情绪障碍。因此,慢性偏头痛应从风、从湿、从瘀、从虚、从郁综合治疗。
Abstract:
Objective To explore the clinical curative effect of ToutongXinNO. 1(TX1) in treating patients with chronic migraine headaches. Methods 80 cases of chronic migraine(CM) patients were randomly divided into two groups, evaluating the degree of anxiety and depression of patients with CM by Self-rating Anxiety Scale(SAS) and Self-rating Depression Scale(SDS), the treatment group who received TX1; and the control group who received FlunarizineHydrochloride Capsules. The treatment lasted for 12 weeks. To observe the difference in two groups. Results There were significantly differences between two groups(P<0.001) in degree, frequency, and duration, before and after the therapy. The effective rates of clinical effect were 95% and 70% in treatment group and control group respectively, the difference was statistically significant(P<0.05). After the therapy, the treatment group had the marked decrease in SAS and SDS(P<0.001), and no marked difference in the control group(P>0.001). Conclusion TX1 is Significantly effective in treating CM, and reducing the depression. CM should be treated based on wind, dampness, blood stasis, deficiency, and the depression.

参考文献/References

[1] Bigal M E,Serrano D,Buse D,et al. Acute Migraine Medications and Evolution From Episodic to Chronic Migraine:A Longitudinal Population-Based Study[J]. Headache:The Journal of Head and Face Pain 2008,48(8):1157-1168.
[2] Straube A,Pfaffenrath V,Ladwig K,et al. Prevalence of chronic migraine and medication overuse headache in Germany—the German DMKG headache study[J]. Cephalalgia 2009,30(2):207-213.
[3] 李凤鹏,王而强,何超,等. 慢性偏头痛和发作性偏头痛临床特点的研究[J]. 临床内科杂志,2013,30(10):677-679.
[4] 谢颖兰,丁砚兵. 慢性偏头痛合并焦虑抑郁的机理探讨[J]. 湖北中医杂志,2014,36(10):28.
[5] 商建青,伍志勇,黄小星,等. 头痛新一号治疗偏头痛66例[J]. 医药导报,2014,33(2):191-193.
[6] Lipton R B. Chronic Migraine,Classification,Differential Diagnosis,and Epidemiology[J]. Headache:The Journal of Head and Face Pain 2011,51:77-83.
[7] 郑筱萸. 中药新药临床研究指导原则(试行)[M]. 北京:中国医药科技出版社,2002:105-109.
[8] 胡小怀. 欣百达防治伴有焦虑抑郁障碍的慢性偏头痛的疗效[J]. 实用医学杂志,2010,26(13):2392-2394.
[9] 葛鑫宇,陈宝田,龙亚秋,等. 头痛方加减治疗偏头痛66例[J]. 安徽中医学院学报,2009,28(3):17-18.
[10] 王奎云,谢勇,周冀英,等. 偏头痛慢性转化的研究现状[J]. 中国疼痛医学杂志,2012,18(11):693-695.
[11] 李旋珠,李文军. 试析附子的临床运用[J]. 云南中医学院学报,2011,34(1):39-42.
[12] 熊海霞,杨颖,孙文燕. 附子多糖的药理作用研究进展[J]. 世界科学技术-中医药现代化,2013,15(9).
[13] 郑琳颖,潘竞锵,吕俊华,等. 白芍总苷药理作用研究[J]. 广州医药,2011,42(3):66-68.

备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(81202687);广东省科技计划项目(2012B061700018) 收稿日期: 2014 - 12 - 02 作者简介: 姜婷婷(1988-),女,湖南邵东人,在读硕士研究生,研究方向:中西医脑病方向。 △通信作者:陈宝田,E-mail:chenbaotian_138@163.com
更新日期/Last Update: 2014-12-20