我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

温中运脾补肾法治疗2型糖尿病临床研究(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2015年02期
页码:
65-68
栏目:
临床研究
出版日期:
2015-04-25

文章信息/Info

Title:
Therapeutic Effect of Middle-warming and Spleen-strengthening and Kidney-tonifying Therapy for Type 2 Diabetes Mellitus
作者:
马春玲阮永队陈红梅
广东省东莞市塘厦医院中医科,广东 东莞,523721
Author(s):
MA Chun-ling RUAN Yong-duiCHEN Hong-mei
Dept.of TCM,Tangxia Hospital of Dongguan,Dongguan 523721 ,China
关键词:
2型 糖尿病 温中运脾补肾法 临床研究 中医疗法
Keywords:
Type 2 diabetes mellitus middle-warming and spleen-strengthening and kidney-tonifying therapy clinical study
分类号:
R255.4
DOI:
-
文献标识码:
A
摘要:
目的观察温中运脾补肾法中药对2型糖尿病患者血糖、血脂、胰岛素敏感性、体重指数方面的作用。方法将105例2型糖尿病患者按2:1比例随机分为中药组70例和对照组(二甲双胍组)35例,疗程均为8周。比较两组血糖、糖化血红蛋白、血脂、空腹胰岛素、胰岛素敏感指数、体重指数的变化。 结果中药组治疗后胰岛素敏感性和高密度脂蛋白胆固醇提高(P<0.05);空腹血糖、餐后2h血糖、糖化血红蛋白、甘油三酯、高空腹胰岛素、体重指数降低(P<0.05)。与对照组比较,降低空腹血糖、餐后2h血糖、糖化血红蛋白的作用相当(P>0.05),而降低甘油三酯、高空腹胰岛素、体重指数,提高胰岛素敏感性和高密度脂蛋白胆固醇的疗效,中药组则优于对照组(P<0.05)。 结论 温中运脾补肾法中药治疗2型糖尿病有较好疗效。
Abstract:
Objective To observe the effect of middle-warming and spleen-strengthening and kidney-tonifying therapy on lowering glucose, regulating blood lipid, increasing insulin sensitivity and decreasing body mass index in type 2 diabetes mellitus patients. Methods 105 cases of patients with type 2 diabetes, according to the proportion of 2:1 were randomly divided into the Chinese medicine group of 70 cases and the control group (metformin group) 35 cases. The course of treatment lasted 8 weeks. Blood glucose, glycosylated hemoglobin, blood lipids, fasting insulin, insulin sensitivity index and body mass index were observed in the two groups before and after intervention. Results After treatment insulin sensitivity and high density lipoprotein cholesterol were improved in the Chinese medicine group(P<0.05). Blood glucose, glycosylated hemoglobin, triglycerides, high fasting insulin and body mass index decreased in the Chinese medicine group(P<0.05). Compared with the control group, the effect on lowering the fasting blood glucose, 2-hour postprandial glucose and glycosylated hemoglobin were equivalent(P>0.05). While the effect on lowering triglycerides, high fasting insulin and body mass index as well as improving the efficacy of insulin sensitivity and high density lipoprotein cholesterol, the Chinese medicine group is better than the control group(P<0.05). Conclusion Middle-warming and spleen-strengthening and kidney-tonifying therapy exerts better curative effect for T2DM patients.

参考文献/References

[1] 汝荣立. 关于糖尿病的新诊断标准与分型. WHO专家咨询报告:糖尿病的定义、诊断、分型与糖尿病并发症[J]. 中国糖尿病杂志,2000,8(1):3-6.
[2] 李秀钧. 胰岛素抵抗综合征[M]. 北京:人民卫生出版社,2001:22-24.
[3] 廖二元,莫朝晖. 内分泌学[M]. 2版.北京:人民卫生出版社,2010:1383.
[4] 李关伟,潘孝仁,Lilliojas,等. 检测人体胰岛素敏感性的一项新指标[J]. 中华内科杂志,1993,32(10):656-660.
[5] Xu Y,Wang L,He J,et al. 2010 China Noncommunicable Disease SURveillance Group. Prevalence and control of diabetes in Chinese adults[J]. JAMA,2013,310:948-959.
[6] 中华医学会糖尿病学分会. 中国2型糖尿病防治指南(2013年版)[J]. 中华糖尿病杂志,2014,6(7):447-498.
[7] 廖二元,莫朝晖. 内分泌学[M]. 2版. 北京:人民卫生出版社,2010:1362-1363.
[8] 马春玲,朱章志,阮永队. 2型糖尿病中医始发病机的临床研究[J]. 新中医,2011,43(6):28-31.
[9] 马春玲,朱章志,阮永队. 从六经辨证之三阴病干预IGR大鼠的实验研究[J]. 齐齐哈尔医学院学报,2011,32(13):2053-2055.
[10] 阮永队,马春玲,陈红梅,等. 温阳健脾法治疗2型糖尿病胰岛素抵抗70例临床研究[J]. 广州中医药大学学报,2011,28(2):113-116.
[11] 高宗磊,柴可夫,方燕旎. 代谢综合征的病因病机探讨[J]. 云南中医学院学报,2014,37(2):28-30.
[12] 张锡纯. 医学衷中参西录(上册)[M]. 河北:河北科学技术出版社,1991:79.

备注/Memo

备注/Memo:
基金项目: 广东省中医药局科研课题(2007284) 收稿日期: 2015 - 01 - 09 作者简介: 马春玲(1978-),女,黑龙江齐齐哈尔人,博士,副主任中医师,主要从事内分泌、代谢性疾病及疑难杂病的中医临床研究,E-mail:chunlingma093@163.com。
更新日期/Last Update: 2015-04-30