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|本期目录/Table of Contents|

清化痰瘀方联合易善复治疗非酒精性脂肪性肝炎的疗效观察(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2015年05期
页码:
61-64
栏目:
临床研究
出版日期:
2015-09-25

文章信息/Info

Title:
The Clinical Observation of Qinghuatangyu Decoction Combined with Essentialeonthe Rehabilitation Treatment of Nonalcoholic Fatty Liver Disease
作者:
杨将领张斌
上海中医药大学附属曙光医院肝病科,上海 201203
Author(s):
YANG Jiangling ZHANG Bin△
Division of Liver Diseases, Shuguang Hospital Affiliated to Shanghai University ofTraditional Chinese Medicine, Shanghai 201203, China
关键词:
清化痰瘀方 非酒精性脂肪性肝炎 中医药疗法
Keywords:
Qinghuatangyu decoction nonalcoholic fatty liver disease traditional Chinese medicine therapy
分类号:
R256.4
DOI:
-
文献标识码:
A
摘要:
目的观察清化痰瘀方治疗非酒精性脂肪性肝炎的临床疗效。方法将60例患者随机分为2组,治疗组30例给予清化痰瘀方合多烯磷脂酰胆碱胶囊(易善复)治疗,对照组30例给予易善复治疗,2组疗程为6个月。观察2组患者治疗前后症状的改善情况、肝功能、血脂以及肝/脾CT比值。2组患者在用药治疗期间均适当加强体育锻炼及控制饮食。结果治疗组总有效率为86.7%,对照组总有效率为73.3%,治疗组优于对照组(P<0.05)。2组治疗6个月后ALT、AST、GGT、TC、HDL-C、UA、TNF、肝/脾CT比值的变化,治疗组优于对照组(P<0.05)。结论清化痰瘀方治疗非酒精性脂肪性肝炎具有良好的临床疗效,可明显改善患者中医症候、肝功能、血脂、血清尿酸、肿瘤坏死因子、肝/脾CT比值。
Abstract:
Objective To observe the clinical curative effect of Qinghuatangyu decoction on the rehabilitation treatment of nonalcoholic fatty liver disease. Methods 60 cases of patients were randomly divided into the treatment group and the control group on average, the treatment group given 6 months’ treatment of Qinghuatangyu decoction combined with polyene phosphatidylcholine capsules(Essentiale), the control group was given only 6 months’ treatment of Essentiale. Observe both of two groups’ improvements of the symptoms, the liver function, blood lipid and liver/spleen CT ratio in pretherapy and post-treatment. The patients of two groups were suitable to enhance physical exercise and control diet during treatment. Results The total effective rates of treatment group and control group were 86. 7% and 73. 3% respectively, the treatment group is better than that of control group(P<0.05). After treatment for 6 months, the changes of treatment group’s ALT, AST, GGT、 TC、 HDL-C、 UA、 TNF, liver/spleen CT ratio are better than that of control group(P<0.05). Conclusion There is a better clinical curative effect of Qinghuatangyu decoction on the rehabilitation treatment of nonalcoholic fatty liver disease, which can significantly improve the patients’ TCM symptoms, liver function, blood fat, serum uric acid, tumor necrosis factor and liver/spleen CT ratio.

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备注/Memo

备注/Memo:
基金项目: 上海市卫生局中医药科研项目(2012L023A) 收稿日期: 2015 - 08 - 03 作者简介: 杨将领(1985-),女,云南大理人,在读博士研究生,研究方向:中西医结合防治慢性肝病。△通信作者:张斌,E-mail:zhangbsh@126.com
更新日期/Last Update: 2015-09-20