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活血化瘀法预处理对输卵管性不孕体外受精-胚胎移植(IVF-ET)妊娠结局的影响(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2016年05期
页码:
62-64,73
栏目:
临床研究
出版日期:
2016-10-10

文章信息/Info

Title:
Effect of Promoting Blood Circulation and Removing Blood Stasis on the Outcome of IVF-ET Pregnancy Outcome in Infertile Women with Tubal Infertility
作者:
刘瑞华12吴丽敏2乔宗惠12庞丽娥12童先宏2刘雨生2
1. 安徽中医药大学,安徽 合肥 230038;2. 安徽省立医院生殖中心,安徽 合肥 230001
Author(s):
LIU Ruihua12 WU Limin2 QIAO Zonghui12 PANG Lie12 TONG Xianhong2 LIU Yusheng2
1. Anhui University of Chinese Medicine, Hefei 230038, China;2. Provincial Hospital of Anhui Medical University, Hefei 230001, China
关键词:
输卵管性不孕症 活血化瘀 体外受精-胚胎移植
Keywords:
tubal Infertility promoting blood circulation and removing blood-stasis in vitro fertilization-embryo transfer
分类号:
R271.14
DOI:
10.19288/j.cnki.issn.1000-2723.2016.05.016
文献标识码:
A
摘要:
目的〓观察中药活血化瘀法预治疗对体外受精-胚胎移植超促排卵周期妊娠结局的影响。方法〓将413例因输卵管因素行IVF-ET的患者随机分为中药+控制性超促排卵组198例(试验组)和单纯控制性超促排卵组215例(对照组)。观察两组生化妊娠率,临床妊娠率,活产率,流产率,异位妊娠率等,做相关性分析。结果〓试验组和对照组生化妊娠率分别为61.11%和58.14%(P>0.05);临床妊娠分别为56.57%和55.81%(P>0.05);活产率分别为51.52%和45.58%(P>0.05);宫外孕妊娠率分别为0.89%和1.67%(P>0.05);流产率分别为8.04%和16.67%(P<0.05)。结论〓对输卵管性不孕行IVF-ET患者用中药活血化瘀法预处理可降低输卵管性不孕患者IVF-ET中的流产率,但对生化妊娠率、临床妊娠率、活产率、异位妊娠率无明显影响。
Abstract:
Objective To observe the effect of promoting blood circulation and removing blood-stasis pretreatment method of traditional Chinese medicine(TCM) therapy on pregnancy outcome concerning the patients who take IVF-ET due to tubal infertility. Methods The patients who take IVF-ET with tubal infertility were randomly divided into traditional Chinese medicine + controlled ovarian hyperstimulation group 198 cases(experimental group) and simple controlled ovarian hyperstimulation group 215 cases(control group). To observe the two groups of biochemical pregnancy rates, clinical pregnancy rates, live birth rates, abortion rates, ectopic pregnancy rates, and so on, and do the correlation analysis. Results The experimental group and the control group biochemical pregnancy rates were 61.11% and 58.14%, respectively(P>0.05); clinical pregnancy rates were 56.57%, and 55.81%, respectively(P>0.05); live birth rates were 51.52% and 45. 58%, respectively(P>0.05); ectopic pregnancy rates were 0.89% and 1.67% respectively(P>0.05); abortion rates were 8. 04% and 16.67% respectively(P<0.05). Conclusion The method of promoting blood circulation and removing blood-stasis can reduce the abortion rate of the patients who take IVF-ET due to tubal infertility, but on biochemical pregnancy rate, clinical pregnancy rate, live birth rate, ectopic pregnancy rate had no significant effect.

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备注/Memo

备注/Memo:
* 基金项目: 国家自然科学基金(81373671) 收稿日期: 2016 - 07 - 19 作者简介: 刘瑞华(1989-),女,河南周口人,在读硕士研究生,研究方向:不孕不育、生殖医学。△通信作者:吴丽敏,E-mail:wuliminmail@126.com
更新日期/Last Update: 2016-10-10