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加味香砂六君子汤对大肠癌术后化疗患者生存质量的影响(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2017年01期
页码:
37-40
栏目:
临床研究
出版日期:
2017-02-20

文章信息/Info

Title:
The Influence of Modified Xiangsha Liujunzi Decoction for Patients of PostoperativeColorectal Cancer on Quality of Life
作者:
仝欣徐川李敏于小伟方美花陶智会
上海市嘉定区中医医院肿瘤科,上海 201800
Author(s):
TONG XinXU ChuanLI MinYU XiaoweiFANG MeihuaTAO Zhihui
Department of Oncology, Jiading Hospital of Traditional Chinese Medicine, Shanghai 201800, China
关键词:
大肠癌 加味香砂六君子汤 生存质量 中医治疗
Keywords:
colorectal cancer Modified Xiangsha Liujunzi Decoction quality of life traditional Chinese medicine treatment
分类号:
R273
DOI:
10.19288/j.cnki.issn.1000-2723.2017.01.009
文献标识码:
A
摘要:
目的 探讨加味香砂六君子汤对大肠癌术后化疗生存质量的影响。方法 78例大肠癌术后患者随机分成治疗组、对照组(每组39例)。对照组采取常规化疗方案(至少连用6个周期),治疗组在常规化疗同时,口服加味香砂六君子汤。治疗前后采用“肿瘤生命质量核心问卷”(QLQ-C30)评估生存质量,并比较两组患者的化疗完成率。结果 治疗组化疗完成率明显高于对照组(P<0.05)。治疗结束时,治疗组“情绪功能”“恶心与呕吐”“食欲丧失”“腹泻”明显优于对照组(P<0.01),治疗组“疲倦”也较对照组有显著改善(P<0.05)。结论 加味香砂六君子汤可以提高大肠癌术后化疗患者生存质量,并有助于患者完成化疗。
Abstract:
Objective To investigate quality of life effects in the treatment of Modified Xiangsha Liujunzi Decoction for patients of postoperative colorectal cancer. Methods A total of 78 cases of the patients of post-operation colonic cancer were randomly divided into treatment group and control group two groups, each 39 cases. The two groups were both treated with chemotherapy for 6 cycles of continuous treatment at least, and the treatment group was additionally treated with Modified Xiangsha Liujunzi Decoction. The quality of life was assessed and compared before and after treatment by Core quality of life questionnaire(QLQ-C30). Chemotherapy completion rate and quality of life were observed. Results Chemotherapy completion rate in the treatment group was higher than that in the control group(P<0.05). After treatment, symptoms(emotion function, nausea and vomiting, loss of appetite, diarrhea) has improved in the treatment group, and the difference was statistically significant(P<0.01). Compared with the control group, significantly improved quality of life in aspects of fatigue in the treatment group, and the difference was statistically significant(P<0.05). Conclusions Modified Xiangsha Liujunzi Decoction can improve the life quality of the patients, successfully finished the chemotherapy.

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备注/Memo

备注/Memo:
* 基金项目: 上海市嘉定区卫生和计划生育委员会中医药科研项目(2014-KY-ZYY-01);上海市嘉定区中医医院重点专
科建设项目(2012-ZD02);上海市嘉定区中医医院李敏主任中医工作室建设项目
收稿日期: 2016 - 12- 25
作者简介: 仝欣(1982-),女,山西临汾人,医学博士,主治医师,研究方向:肿瘤疾病的中医药治疗。
E-mail:tongxinfangyan@126.com
更新日期/Last Update: 2017-02-10