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|本期目录/Table of Contents|

基于数据挖掘的糖尿病足中药熏洗处方用药规律研究(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2017年03期
页码:
87-90
栏目:
方药研究
出版日期:
2017-07-17

文章信息/Info

Title:
Study on Medication Rules of Herbal Fumigation and Washing Prescriptionfor Diabetic Foot Based on Data Mining
作者:
何伟柳国斌△张定棋李文惠毛丽萍黄海
上海中医药大学附属曙光医院,上海 201203
Author(s):
HE WeiLIU GuobinZHANG DingqiLI WenhuiMAO LipingHUANG Hai
Shuguang Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China
关键词:
糖尿病足 中药熏洗 数据挖掘 用药规律
Keywords:
diabetic foot Chinese herbal fumigation and washing data mining medication regularity
分类号:
R244.9;R269
DOI:
10.19288/j.cnki.issn.1000-2723.2017.03.021
文献标识码:
A
摘要:
目的 利用中医传承辅助平台(TCMISS V1.1)中的频数统计、关联规则、关联度分析、药物核心组合分析及无监督熵层次聚类算法,获得治疗糖尿病足中药熏洗处方的核心药物、核心组合及新处方。结果 对筛选出的95个处方进行统计,使用频次前10位的是红花、桂枝、鸡血藤、当归、赤芍、川牛膝、川芎、透骨草、桃仁、黄芪。药物组合使用频次由高到低排序,前3组分别是“红花、桂枝”,“当归、红花”,“红花、鸡血藤”。并挖掘出治疗糖尿病足的中药熏洗方的核心组合16个和8首可能具有临床价值的新处方。结论 目前治疗糖尿病足的中药熏洗方多以活血止痛、舒筋通络药为主,并通过数据挖据初步探索出了中药熏洗处方的主要药物组成为当归、红花、桂枝、黄芪、川芎、透骨草、赤芍、桃仁、乳香、没药、鸡血藤、川牛膝等。根据不同证型可以进一步探讨新方的临床价值。
Abstract:
Objective To use TCM inheritance auxiliary system(TCMISS V1. 1) in the frequency statistics, association rules, correlation analysis, drug core combination analysis and unsupervised hierarchical clustering algorithm to obtain the entropy, traditional Chinese medicine in the treatment of diabetic foot washing prescription drugs, smoked core core combinations and new prescription. Results The statistics of the 95 prescriptions, the frequency of use of the top 10 are safflower, angelica, cassia twig, Caulis Spatholobi, radix paeoniae rubra, Rhizoma Chuanxiong, Radix cyathulae, lopseed, peachseed, huangqi. Combination of drugs use frequency from high to low ranking, the first 3 groups were “safflower Guizhi”, “angelica, safflower”, “safflower, Caulis Spatholobi”. And dig out the core combination of herbal fumigation and washing prescription for treating diabetic foot, 16 and 8 new prescriptions that may have clinical value. Conclusion The traditional Chinese medicine in the treatment of diabetic foot fumigation in Huoxue Zhitong, Shujin Tongluo medicine, and through data mining initially explored the main drug fumigation of Chinese medicine prescription composition:Angelica, safflower, astragalus, Guizhi, Rhizoma Chuanxiong, radix paeoniae rubra, lopseed, walnuts, milk incense, myrrh, Caulis Spatholobi. Cyathula etc.. The clinical value of the new method can be further explored according to different syndrome types.

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备注/Memo

备注/Memo:
* 基金项目: 上海市科学技术委员会科研计划项目(16401902200)
收稿日期: 2017 - 05- 19
作者简介: 何伟(1992-),女,湖北宜昌人,在读硕士研究生,研究方向:中西医结合治疗周围血管疾病。
△通信作者:柳国斌,E-mail:drliuguobin@163.com
更新日期/Last Update: 2017-06-20