我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

腓骨近端截骨术联合丹紫康膝冲剂内服治疗肾虚髓亏型膝骨关节炎的疗效观察(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2017年04期
页码:
63-66
栏目:
临床研究
出版日期:
2017-10-20

文章信息/Info

Title:
Clinical Observation on the Treatment of Knee Osteoarthritis with Proximal FibulaOsteotomy Combined with Danzi Kangxi Granules
作者:
周彪12熊辉2郭玉星3向黎黎3徐云1陆小龙3
1. 湘潭市第一人民医院,湖南 湘潭 411101;2. 湖南中医药大学,湖南 长沙 410208;3. 湖南中医药大学第二附属医院,湖南 长沙 410005
Author(s):
ZHOU Biao1 2 XIONG Hui2 GUO Yuxing3 XIANG Lili3 XU Yun1 LU Xiaolong3
1. The First People’s Hospital of Xiangtan, Xiangtan 411101, China;2. Hunan University of Chinese Medicine, Changsha, 410208, China;3. The Second Hospital Affiliated to Hunan University of Chinese Medicine, Changsha 410005, China
关键词:
骨关节炎 膝关节 丹紫康膝冲剂 腓骨近端截骨术
Keywords:
osteoarthritis knee joint Danzi Kangxi Granules proximal fibular osteotomy
分类号:
R274.9
DOI:
10.19288/j.cnki.issn.1000-2723.2017.04.015
文献标识码:
A
摘要:
目的 观察腓骨近端截骨术联合中药复方丹紫康膝冲剂治疗肾虚髓亏型膝关节骨关节炎的临床疗效。方法 将60例膝关节骨关节炎(单侧内翻型)患者随机分为两组,即对照组和治疗组,每组各30例。对照组行近端腓骨截骨术,术后常规使用消肿、抗炎镇痛类药物和局部理疗;治疗组在对照组干预的基础上于术后第2天开始加用中药复方丹紫康膝冲剂口服,1周为1个疗程。2组均治疗1个疗程。术后3周随访,比较2组VAS评分、JOA关节功能评分和临床疗效。结果 术后3周,治疗组的VAS评分及JOA关节功能评分均明显高于对照组,临床有效率明显高于对照组,差异均有统计学意义(P<0.05)。结论 中药复方丹紫康膝冲剂治疗内翻型膝关节骨关节炎(肾虚髓亏型)可有效缓解患者关节疼痛、肿胀及功能障碍等临床症状,提高关节功能评分。
Abstract:
Objective To observe the clinical effect of proximal fibular osteotomy combined with Danzi Kangxi Granules in treating osteoarthritis of the knee. Methods 60 patients with osteoarthritis of the knee were randomly divided into control group and treatment group(n=30). The control group underwent proximal fibula osteotomy, postoperative routine use of detumescence, anti-inflammatory and analgesic drugs and topical therapy. The treatment group was treated with Chinese herbal compound danzikangxi granules orally started on the basis of the control group on the second day after surgery, 1 week for 1 course. 2 groups were treated for 1 course. 3 weeks after operation, the VAS score, JOA joint function score and clinical efficacy were compared between the 2 groups. Results After 3 weeks, the VAS score and JOA joint function score of the treatment group were significantly higher than those of the control group, the clinical effective rate was significantly higher than that of the control group, the difference was statistically significant(P<0.05). Conclusion The Danzi Kangxi granules can effectively relieve the knee joint pain, swelling and dysfunction and improve the joint function score.

参考文献/References

[1] 张英泽,李存祥,李冀东,等. 不均匀沉降在膝关节退变及内翻过程中机制的研究[J]. 河北医科大学学报,2014,35(2):218-219.
[2] 赵新文,李钊,丁勇,等. 胫骨高位截骨治疗膝关节骨性关节炎临床疗效分析[J]. 中国骨与关节损伤杂志,2016,31(12):1272-1276.
[3] Jevsevar DS. Treatment of osteoarthritis of the knee:evidence- based guideline[J]. J Am Acad Orthop Surg,2013,21(9):571-576.
[4] 国家中医药管理局. 中医病证诊断疗效标准[S]. 南京:南京大学出版社,1994:56.
[5] 吴向科,童培建,陈志进. 膝关节骨性关节炎中西医结合治疗的临床疗效研究分析[J]. 中华中医药学刊,2015,33(4):999-1001.
[6] 郑筱萸. 中药新药临床研究指导原则(试行)[M]. 北京:中国医药科技出版社,2002:329.
[7] 祁昕征,张家铭,谭传明,等. 从生物力学角度评价单髁置换术与腓骨截骨术[J]. 医用生物力学,2015,30(6):479-487.
[8] Zhou B,Lu X,Tang Z,et al. Influence of sinomenine upon mesenchymal stem cells in osteoclastogenesis[J]. Biomed Pharmacother,2017,90:835-841.
[9] 李存祥,贾素华,王健,等. 单纯腓骨截断术治疗膝关节骨关节炎临床研究[J]. 中国医学创新,2010,7(2):115-117.
[10] 刘经端,古恩鹏. 运用现代中医思维方法探索性推论腓骨截骨术防治膝骨性关节炎的原理[J]. 中华中医药杂志,2016,31(12):5134-5136.
[11] 马卫华,张树栋,王诗军,等. 腓骨高位截骨治疗膝关节骨关节炎机理探讨[J]. 中华关节外科杂志(电子版),2015,9(3):421-422.
[12] 王斌. 中医对骨性关节炎病因病机的认识及治疗[J]. 中医临床研究,2011,3(4):118.
[13] 刘向前,姚共和. 膝关节骨关节炎中医病证名称及中药治疗现状述评[J]. 中医正骨,2004,16(4):53-54.
[14] 周昭辉,陆小龙,孙绍裘,等. 丹紫康膝冲剂治疗膝关节骨性关节炎90例临床观察[J]. 中医药导报,2008,14(8):47-48.
[15] 许小桦,孙绍裘,王勇,等. 自制丹紫康膝冲剂治疗膝关节骨性关节炎的临床研究[J]. 临床和实验医学杂志,2009,8(5):119-120.
[16] 豆贲,王志伟,谢义松,等. 丹紫康膝冲剂治疗膝骨性关节炎30例总结[J]. 湖南中医杂志,2015,31(5):78-79.

备注/Memo

备注/Memo:
* 基金项目: 湖南省自然科学基金(S2013J5043)
收稿日期: 2017 - 06- 23
作者简介: 周彪(1986-),男,湖南湘潭人,博士,主治医师,研究方向:筋伤与骨病的中医药防治。
△通信作者:陆小龙,E-mail:1730657921@qq.com
更新日期/Last Update: 2017-08-30