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|本期目录/Table of Contents|

血府逐瘀汤加减治疗对髋关节置换术后患肢肿胀和血小板、D-二聚体的影响*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2018年03期
页码:
73-76
栏目:
临床研究
出版日期:
2018-12-15

文章信息/Info

Title:
Effect of Xuefu Zhuyu Decoction in the Treatment of Limb Swelling and Platelet and D-two Polymer after Hip Replacement
作者:
孙芳芳董宪传杨永菊
(辽宁中医药大学附属医院,辽宁 沈阳 110032)
Author(s):
SUN Fangfang DONG Xianchuan YANG Yongju
(Affiliated Hospital of Liaoning University of Traditional Chinese Medicine, Shenyang 110032, China)
关键词:
血府逐瘀汤 髋关节置换 患肢肿胀 血小板 D-二聚体
Keywords:
Xuefu Zhuyu Decoction hip joint replacement limb swelling platelet D-two polymer
分类号:
R274.9
DOI:
10.19288/j.cnki.issn.1000-2723.2018.03.017
文献标识码:
A
摘要:
目的观察血府逐瘀汤加减治疗髋关节置换术后对患者患肢肿胀和血小板、D-二聚体的影响。方法选择全髋关节置换 术患者118例,随机分为观察组61例、对照组57例,对照组术后给予常规深静脉血栓(DVT)预防方案,在此基础上观察组 给予血府逐瘀汤加减治疗,比较2组患肢肿胀程度、血小板活性化、血浆D-二聚体、患肢静脉血流速度以及DVT发生率。结 果术后3d、术后7 d两组患者患肢肿胀程度均较术前、术后1 d明显降低(P<0.05),且术后3 d、术后7 d观察组患者患肢 肿胀程度显著低于对照组(P<0.05)。2组患者术后3 d、术后7 d血小板活化指标GP IIb/IIIa与GMP-140均较术后1 d显著 降低(P<0.05),且观察组低于对照组(P<0.05)。术后3 d、术后7 d两组患者血浆D-二聚体水平较术后1 d显著降低 (P<0.05),且观察组低于对照组(P<0.05)。观察组术后DVT发生率低于对照组,但差异无统计学意义(P>0.05)。结论 血府逐瘀汤可有效减轻髋关节置换术后患者患肢肿胀程度、降低血小板活化以及血浆D-二聚体水平,改善机体高凝状态, 有效预防DVT发生。
Abstract:
Objective The effects of Xuefu Zhuyu Decoction plus subtraction on limb swelling and platelet and D-two polymer after hip replacement were analyzed and analyzed. Methods 118 cases of total hip replacement in our hospital were randomly divided into 61 cases in the observation group and 57 cases in the control group. The control group was given the routine deep vein thrombosis(DVT) prevention program after operation. On this basis, the observation group gave the Xuefu Zhuyu Decoction plus subtraction treatment, and compared the degree of swelling of the limbs, platelet activation and plasma D-two polymer in the two groups. The velocity of venous blood flow in the affected limb and the incidence of DVT. Results after operation 3 d and 7 d, the swelling degree of the affected limbs was significantly lower than that before and after the operation(P<0.05), and after after operation 3 d and 7 d the degree of swelling of the affected limbs observation group was significantly lower than that of the control group(P<0.05). after operation 3 d and 7 d, the platelet activation index of GP IIb/IIIa and GMP-140 after operation in the observation group were significantly lower than that of postoperative 1 d (P<0.05), and the observation group was lower than that of the control group(P<0.05). The levels of plasma D-dimer in two groups after operation 3 d and 7 d lower than those after operation 1 d(P<0.05), and the observation group was lower than the control group(P<0.05). The total vein of limb femoral vein and deep femoral vein blood flow rate in the two groups after 3 d and 7 d after operation were significantly higher than that before operation(P<0.05), and the observation group was significantly higher than that of the control group(P<0.05). The incidence of postoperative DVT in the observation group was lower than that in the control group, but the difference was not statistically significant(P>0.05). Conclusion Xuefu Zhuyu Decoction can effectively reduce the degree of limb swelling, decrease the activation of platelet and the level of plasma D-two polymer after hip replacement, improve the hypercoagulability of the body, and promote the velocity of venous blood flow after the operation, thus effectively preventing the occurrence of DVT.

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备注/Memo

备注/Memo:
收稿日期: 2018 - 06- 15 *
基金项目: 2015年中医药行业科研专项项目(201507006)
第一作者简介: 孙芳芳(1982-),女,硕士,主治医师,研究方向:骨伤病的康复治疗。
更新日期/Last Update: 2018-12-30