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电针长强穴对缺血缺氧脑损伤大鼠发育的影响*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2018年01期
页码:
25-28
栏目:
实验研究
出版日期:
2018-06-30

文章信息/Info

Title:
Effect on Development of Electroacupuncture Changqiang Point in HIBD Rats
作者:
黄倩茹1萨喆燕1潘晓华1万 隆1张学君2许金森1
(1. 福建省中医药研究院,福建 福州 350003;2. 福建中医药大学,福建 福州 350122)
Author(s):
HUANG Qianru1 SA Zheyan1 PAN Xiaohua1 WAN Long1 ZHANG Xuejun2 XU Jinsen1
(1. Fujian Academy of Traditional Chinese Medicine, Fuzhou 350003, China; 2. Fujian University of Chinese Medicine, Fuzhou 350122, China)
关键词:
缺血缺氧脑损伤长强穴体质量测评睁眼时间评定
Keywords:
HIBD Changqiang point weight measurement open time to assess
分类号:
R285.5
DOI:
10.19288/j.cnki.issn.1000-2723.2018.01.006
文献标识码:
A
摘要:
目的观察电针长强穴对缺血缺氧脑损伤大鼠体质量及睁眼时间的影响,探讨新生儿缺血缺氧性脑损伤(HIBD)的有效干预措施。方法随机挑选新生PN7(postnatal 7day,PN7)SD仔鼠32 只,其中24 只予左侧颈总动脉结扎、剪断及缺氧后制备缺血缺氧大鼠,并分为模型组、电针长强组(长强组)、电针非穴组(非穴组)各8只,另8只分离左侧颈总动脉但不结扎剪断,亦不做缺氧处理作为假手术组。长强组取长强穴,电针刺激(连续波,频率为2 Hz,强度为2 mA)20 min,连续治疗10 d为1个疗程,共1 个疗程;非穴组取大鼠右胁肋下缘一横指处,余操作同长强组;空白组和模型组在相同环境下饲养,不予干预;对各组大鼠的体质量及睁眼时间进行记录并分析。结果①体质量测评:PN7~PN13:与假手术组相比,模型组体质量下降,差异无统计学意义(P>0.05)。PN14:与假手术组相比,模型组体质量下降,有显著性差异(P<0.05);与模型组相比,长强组及非穴组体质量上升,差异无统计学意义(P>0.05)。PN15~PN21:与假手术组相比,模型组体质量下降,有显著性差异(P<0.05);与模型组相比,长强组体质量上升,有显著性差异(P<0.05),非穴组体质量上升,差异无统计学意义(P>0.05)。② 睁眼时间评分:与假手术组相比,模型组睁眼日龄下降,有显著性差异(P<0.05);与模型组相比,长强组及非穴组睁眼日龄上升,差异无统计学意义(P>0.05)。结论电针长强穴可促进缺血缺氧脑损伤大鼠体质量趋于正常,为缺血缺氧疾病的有效治疗方式之一。
Abstract:
Objective To observe the curative of ischemia hypoxia increased the weight of rats and the influence of the open time, explore the effective intervention measures of HIBD. Methods Randomly selected PN7(postnatal day 7, PN7) SD wang rat only 32, 24 of them to the left common carotid artery ligation, cutting and preparation after hypoxia ischemia hypoxia in rats, and is divided into model group, electroacupuncture Changqiang group(Changqiang group), non-acupoint electroacupuncture group(non-acupoint group)each for 8, the other 8 separate but not of the left common carotid artery ligation cutting, nor do anoxic treatment as control group. Changqiang group take Changqiang point, electroacupuncture(continuous wave, frequency of 2 hz, strength to 2 ma) 20 min, continuous treatment for 10 days for a period of treatment, a total of one period of treatment;The acupuncture point group take the lateral edge of rats right rib refers to, long residual operation with strong group; The blank group and model group in the same environment, will not be intervention; For each group rats weight and open time for recording and analysis. Results ① The weight assessment: PN7~PN13: compared with control group, model group, weight loss, there was no statistically significant difference(P>0.05). PN14: compared with control group, model group, weight loss, there are significant differences(P<0.05); Compared with model group, weight gain Changqiang group and non-acupoint group, there was no statistically significant difference(P>0.05). PN15~PN21: compared with control group, model group, weight loss, there are significant differences(P<0.05); Changqiang group compared with model group, weight gain, there are significant differences(P<0.05), the non-acupoint group, weight gain, there was no statistically significant difference(P>0.05). ② Open time score:compared with control group, model group opened its eyes fall day age, there are significant differences(P<0.05); Compared with model group, Changqiang open up day age group and the non-acupoint group, there was no statistically significant difference(P>0.05). Conclusion Acusector “Changqiang” can promote HIBD rats weight returns to normal, as one of the effective treatment of HIBD diseases.

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备注/Memo

备注/Memo:
基金项目: 国家自然科学基金(81603543);福建省科技厅省属公益类项目(2016R1033-2);福建省卫计委青年人才项目 (2016-1-82);福州市科技局资助项目(2016-G-70);福建省经络感传重点实验室资助
更新日期/Last Update: 2018-06-30