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|本期目录/Table of Contents|

中药保留灌肠治疗溃疡性结肠炎的系统评价再评价*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2018年06期
页码:
44-49
栏目:
临床研究
出版日期:
2019-09-10

文章信息/Info

Title:
Ulcerative Colitis Treated with Retention-Enema of Chinese Herb: An Overview of Systematic Reviews
文章编号:
1000 - 2723(2018)06- 0044 - 06
作者:
刘洪武1黎丽群1岑前丽1刘园园2刘倩2黄晓燕2谢胜2△
(1. 广西中医药大学研究生院,广西 南宁 530001;2. 广西中医药大学第一附属医院,广西 南宁 530001)
Author(s):
LIU Hongwu1 LI Liqun1 CEN Qianli1 LIU Yuanyuan2 LIU Qian2 HUANG Xiaoyan2 XIE Sheng2
(1. Graduate School of Guangxi University of Traditional Chinese Medicine, Nanning 530001, China;2. The First Affiliated Hospital of Guangxi University of Traditional Chinese Medicine, Nanning 530001, China)
关键词:
溃疡性结肠炎 中药保留灌肠 系统评价 研究方法学 再评价
Keywords:
UC retention-enema of Chinese herb systematic review research methodology overview of systematic review
分类号:
R259
DOI:
10.19288/j.cnki.issn.1000-2723.2018.06.009
文献标识码:
A
摘要:
目的对中药保留灌肠结局指标进行证据质量分级。方法计算机检索中国知网、万方、维普、PubMed数据库,收集公开发表关于中药保留灌肠治疗溃疡性结肠炎的系统评价及Meta分析。结果最终纳入7篇系统评价,所有系统评价均对原始研究进行了偏倚风险评估;AMSTAR2量表显示,所有系统评价均为极低质量;GRADE评级结果显示,共有11个结局指标,其中4个为高等级,1个为中等级,5个为低级别,1个为极低级别。结论目前中药保留灌肠治疗溃疡性结肠炎的临床疗效和安全性比西药有一定优势,中等至高等级的结局指标共有5个,但因系统评价的研究方法学质量处于极低水平,可能会对证据的可信度产生一定的影响。
Abstract:
Objective The aim of this article was to re-evaluate the methodological bias and the reliability of the conclusions of systematic reviews(SRs) of Ulcerative Colitis(UC) treated with Retention-enema of Chinese Herb. Methods CNKI, VIP, Wan Fang Database and Pubmed were electronically searched to collect the published systematic reviews and mete-analyses evaluating Ulcerative Colitis treated with Retention-enema of Chinese Herb. Results A total of 7 relevant SRs/Mets were included. The assessment results of AMSTAR2 tool showed:the quality levels of all the SRs were very low. The results of GRADE showed:the quality of the evidences of 4 outcomes were high and 1 outcome was moderate. 6 outcomes were low or very low. Conclusions The curative effect of treatment group is better than of the control group. The quality level of outcomes from moderate to high were five in total. But the methodological quality of Ulcerative Colitis treated with Retention-enema of Chinese Herb included SRs was very low, which can bring some effects on the reliability of the outcomes.

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备注/Memo

备注/Memo:
收稿日期: 2018 - 12- 15
* 基金项目: 国家自然科学基金面上项目(81573914);2018-2019年研究生教育创新计划项目课题(YCSY20190078)
第一作者简介: 刘洪武(1992-),男,在读硕士研究生,研究方向:脾胃四时调四脏防治疾病的应用。
△通信作者: 谢胜,E-mail:xiesheng2018tougao@163.com
更新日期/Last Update: 2019-07-11