我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

中医外治法治疗正常高值血压的Meta分析*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2019年02期
页码:
31-38
栏目:
临床研究
出版日期:
2019-11-15

文章信息/Info

Title:
Meta-analysis of External Therapy of Traditional Chinese Medicine for High-normal Blood Pressure
文章编号:
1000-2723(2019)02-0031-08
作者:
欧阳雅蓉1黄彩依1傅为武1何亚州1黄景伟1王庆高2△
(1. 广西中医药大学研究生院,广西 南宁 530001;2. 广西中医药大学第一附属医院,广西 南宁 530023)
Author(s):
OUYANG Yarong1HUANG Caiyi1 FU Weiwu1HE Yazhou1HUANG Jingwei1WANG Qinggao2
(1. Guangxi University of Chinese Medicine, Nanning 530001, China;2. The First Affiliated Hospital of Guangxi University of Chinese Medicine, Nanning 530023, China)
关键词:
正常高值血压 中医外治法 Meta分析
Keywords:
high-normal blood pressure external treatment of TCM Meta-analysis
分类号:
R259
DOI:
10.19288/j.cnki.issn.1000-2723.2019.02.007
文献标识码:
A
摘要:
目的系统评价针灸、耳针、艾灸、按摩、足浴、穴位埋线等中医外治法治疗正常高值血压的疗效。方法 计算机检索中国知网、维普网、万方数据库、中国生物医学文献数据库、PubMed、Embase、Cochrane Library等数据库。由2名研究员根据纳排标准独立检索并收集相关文献,使用Cochrane 评价手册对文献进行质量评估。用Revman5.1软件对所提取的数据进行Meta分析。结果 共纳入17个随机对照试验研究,包括1455例病人,其中实验组726例病人,对照组729例病人。Meta分析结果提示:与对照组相比,实验组在降低收缩压[MD=-1.30,95%CI(-1.71,-0.88),P<0.00001]、降低舒张压[MD=-3.13,95%CI(-4.16,-2.09),P<0.00001]、降压治疗效果[RR=1.13,95%CI(1.01,1.28),P=0.05]以及中医症状改善效果[RR=3.07,95%CI(1.90,4.96),P<0.00001]等方面有优势。结论 与单纯生活方式干预或不进行干预对比,中医外治法对治疗正常高值血压有效,但分析结果提示异质性大,所纳入文献质量偏低,结论可靠性仍需通过纳入样本数更大、更高质量随机临床对照试验进一步论证。
Abstract:
Objective To evaluate systematically the efficacy of external treatment of high-normal blood pressure by acupuncture, ear acupuncture, moxibustion, massage, foot bath and acupoint catgut embedding. Methods To search related literatures in Chinese National Knowledge Infrastructure, VIP Web, Wanfang Datebase, SinoMed, PubMed databases, Embase, and Cochrane Library. The two researchers independently and strictly searched and extracted the data according to the standard of include-exclude standard. The quality of the literatures was evaluated by using the Cochrane evaluation manual. The data were analyzed by Revman 5.1 software. Results A total of 17 randomized controlled trials including 1455 patients were included, including 726 patients in the experimental group while 729 patients in the control group. Meta-analysis result: Comparing with the control group, the experimental group had advantages in reducing systolic blood pressure[MD=-1.30, 95%CI (-1.71, -0.88), P<0.00001], diastolic blood pressure[MD=-3.13, 95%CI (-4.16, -2.09), P<0.00001], effective rate of antihypertensive therapy[RR=1.13, 95%CI (1.01, 1.28), P=0.05], and improving TCM symptoms of patients [RR=3.07, 95%CI (1.90, 4.96), P<0.00001]. Conclusion Compared with simple lifestyle intervention or no intervention, external treatment of traditional Chinese medicine is effective in the treatment of High-normal blood pressure, but the analysis results show that the heterogeneity is large, and the quality of the included literature is low. So the reliability of the conclusion still needs to be further demonstrated by the larger sample size and higher quality randomized controlled clinical trials.

参考文献/References

[1] CHOBANIAN A V , BAKRIS G L , BLACK H R , et al. The seventh report of the Joint National Committee on prevention, detection, evaluation and treatment of high blood pressure. The JNC 7 report[J]. Acc Current Journal Review, 2003, 12(4):31-32.
[2] 中国高血压防治指南修订委员会,高血压联盟(中国),中华医学会心血管病学分会,等. 中国高血压防治指南(2018年修订版)[J]. 中国心血管杂志,2019,24(1):24-56.
[3] WANG Z, CHEN Z, ZHANG L, et al. Status of hypertension in China:results from the China hypertension survey,2012-2015[J]. Circulation,2018,137(22):2344-2356.
[4] TURGUNOVA L, KOICHUBEKOV B, TURMUHAMBETOVA A, et al. Biochemical markers of hypertension, prehypertension [J]. Ann Cardiol Angeiol(Paris),2018,67(3):161-166.
[5] JANG S Y, KIM S, LEE C K, et al. Prehypertension and left ventricular diastolic dysfunction in middle-aged Koreans[J]. Korean Circ J,2016,46(4):536-541.
[6] LEITSCHUH M, CUPPLES L A, KANNEL W, et al. High-normal blood pressure progression to hypertension in the Framingham Heart Study[J]. Hypertension,1991,17(1):22-27.
[7] KOKUBO Y, KAMIDE K, OKAMURA T, et al. Impact of high-normal blood pressure on the risk of cardiovascular disease in a Japanese urban cohort:the Suita study[J]. Hypertension,2008,52(4):652-659.
[8] 曾家丽. 中药泡足在阳虚质正常高值血压人群中的应用[J]. 齐鲁护理杂志,2016,22(19):66-67.
[9] 常晓宾,郭珺,杨迪,等. 穴位按摩对大学生高血压前期血压的影响[J]. 现代医药卫生,2016,32(15):2320-2321.
[10] 陈广杰,韩云,商庆新,等. “三才逆灸法”干预高血压前期即刻效应临床观[J]. 特别健康,2018(16):40-44.
[11] 胡蒙蒙,尹莲花,许艺惠,等. 快步走配合穴位贴敷对高血压前期疗效的影响[J]. 湖南中医杂志,2016,32(7):15-17.
[12] 黄春英. 中药泡足干预正常高值血压50例临床观察[J]. 中国民族民间医药,2017,26(8):91-93.
[13] 杨建萍,嵇冰,陆周翔,等. 耳穴压豆防治社区老年人正常高值血压43例临床观察[J]. 浙江中医杂志,2016,51(9):670-671.
[14] 姜海霞,王英灿,商庆新. 三才灸法改善痰湿质高血压前期临床研究[J]. 山东中医药大学学报,2018,42(1):61-63.
[15] 陆周翔,嵇冰. 热敏灸对阴虚质、阳虚质两种体质人群正常高值血压的影响[J]. 上海针灸杂志,2018,37(1):97-100.
[16] 王敏,商庆新,李檬,等. 三才逆灸法治疗痰湿质高血压病前期患者疗效观察[J]. 中医临床研究,2018,10(15):44-46.
[17] 许曼曼. 耳揿针加生活方式干预高血压前期的临床研究[D]. 广州:广州中医药大学,2018.
[18] 赵鑫,刘振岳. 耳穴贴压配合生活方式干预治疗痰瘀互结型高血压前期的临床研究[J]. 中国处方药,2018,16(1):102-103.
[19] 甄毅锋,杜爱平,饶晓平. 针灸联合生活方式干预对高血压前期患者的疗效观察[J]. 医药前沿,2018,8(19):326.
[20] 嵇冰,陆周翔,姚丽娟. 耳穴压豆防治社区老年人正常高值血压42例临床观察[C]//全国卫生产业企业管理协会治未病分会成立大会暨首届“治未病”发展论坛论文集. 北京:全国卫生产业企业管理协会,2015:3.
[21] 谷文龙,柳昌希,王增荣,等. 活血散风针刺法对高血压前期患者血压的影响[J]. 中国中西医结合杂志,2015,35(11):1318-1321.
[22] CHO S H. Effects of moxibustion on physiological indices and autonomic nervous symptoms in adults with prehypertension[J]. Journal of Korean Academy of Nursing,2010,40(5):686-694.
[23] 沈桂琴,刘巧凤,张阿宏,等. 芳香疗法联合刮痧在血压正常高值痰湿质人群中的应用研究[J]. 护理实践与研究,2013,10(19):4-6.
[24] 潘晓涛,高君. 足底敷贴治疗血压正常高值的临床疗效观察[J]. 新疆中医药,2014,32(2):32-34.
[25] 郑筱萸. 中药新药临床研究指导原则(试行)[M]. 北京:中国医药科技出版社,2002:195-201.
[26] BAO X, MENG G, ZHANG Q, et al. Elevated serum complement C3 levels are associated with prehypertension in an adult population[J]. Clin Exp Hypertens,2017,39(1):42-49.
[27] YAO W, SUN Y, WANG X, et al. Elevated serum level of interleukin 17 in a population with prehypertension[J]. J Clin Hypertension(Greenwich),2015,17(10):770-774.
[28] KUWABARA M, HISATOME I, NIWA K, et al. Uric acid is a strong risk marker for developing hypertension from prehypertension:A 5-Year Japanese Cohort Study[J]. Hypertension,2018,71(1):78-86.
[29] WANG Q, HUANG J, SUN Y, et al. Association of microalbuminuria with diabetes is stronger in people with prehypertension compared to those with ideal blood pressure[J]. Nephrology(Carlton),2018,23(7):690-696.
[30] LYU Q S, HUANG Y Q. The relationship between serum total bilirubin and carotid intima-media thickness in patients with prehypertension[J]. Ann Clin Lab Sci, 2018,48(6):757-763.
[31] RUBIO-GUERRA A F, GARRO-ALMENDARO A K, LOZANO-NUEVO J J, et al. Prehypertension is associated with peripheral arterial disease and low ankle-brachial index[J]. Indian Heart J,2018,70(4):502-505.
[32] LI T, YANG J, GUO X, et al. Geometrical and functional changes of left heart in adults with prehypertension and hypertension:a cross-sectional study from China[J]. BMC Cardiovasc Disord,2016,16(28):114.
[33] CUSPIDI C, SALA C, TADIC M, et al. Pre-hypertension and subclinical cardiac damage:A meta-analysis of echocardiographic studies [J]. Int J Cardiol,2018(270):302-308.
[34] ZHANG Z, SHI D, ZHANG Q, et al. Visceral adiposity index(VAI), a powerful predictor of incident hypertension in prehypertensives[J]. Internal and Emergency Medicine,2018,13(4):509-516.
[35] ISHIKAWA Y, ISHIKAWA J, ISHIKAWA S, et al. Progression from prehypertension to hypertension and risk of cardiovascular disease[J]. J Epidemiol,2017,27(1):8-13.
[36] CELIK T, IYISOY A, ACIKEL C, et al. The comparative effects of metoprolol and perindopril on aortic elasticity in young patients with prehypertension[J]. Blood Press Monit,2008,13(3):169-176.
[37] FUCHS F D, FUCHS S C, POLI-DE-FIGUEIREDO C E, et al. Effectiveness of low-dose diuretics for blood pressure reduction to optimal values in prehypertension:a randomized clinical trial[J]. Hypertens,2018,36(4):933-938.
[38] 李洪波. 高血压前期中医药防治的研究进展[J]. 实用心脑肺血管病杂志,2012,20(9):1435-1436.

备注/Memo

备注/Memo:
收稿日期: 2019 - 04- 09
* 基金项目: 广西卫生厅重点课题(重2011058);广西中医药大学2019年研究生教育创新计划项目 ( YCSY20190099)
第一作者简介: 欧阳雅蓉(1994-),女,在读硕士研究生,研究方向:中西医防治心血管疾病。
△通信作者: 王庆高,E-mail:63837132@qq.com
更新日期/Last Update: 2019-11-19