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柔肝方联合恩替卡韦治疗乙肝后肝纤维化的临床观察*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2019年03期
页码:
49-52
栏目:
临床研究
出版日期:
2020-04-20

文章信息/Info

Title:
Clinical Observation of RouGan Decoction Combined with Entecavir in the Treatment of Liver Fibrosis induced by Hepatitis B
文章编号:
1000-2723(2019)03-0049-04
作者:
吴惠春秦爱兰赵卫峰甘建和
(苏州大学附属第一医院感染病科,江苏 苏州 215006)
Author(s):
WU Huichun QIN Ailan ZHAO Weifeng GAN Jianhe
(Department of Infectious Diseases, the First Affiliated Hospital of Suzhou University, Suzhou 215006, China)
关键词:
柔肝方恩替卡韦乙肝后肝纤维化中西医结合疗法
Keywords:
RouGan Decoction entecavir liver fibrosis induced by hepatitis B therapy of integrated medicine
分类号:
R256.43
DOI:
10.19288/j.cnki.issn.1000-2723.2019.03.009
文献标识码:
A
摘要:
目的观察柔肝方联合恩替卡韦治疗乙肝后肝纤维化的临床疗效。方法 选取我院门诊诊治的乙肝后肝纤维化患者60例,随机分为对照组和观察组各30例。对照组予以恩替卡韦治疗,观察组予以柔肝方联合恩替卡韦治疗,疗程为3个月。比较2组患者临床疗效、治疗前后肝功能指标及肝脏弹性值。结果 观察组总有效(86.67%)明显高于对照组总有效率(63.33%);治疗前后比较,观察组肝功能指标、肝脏弹性值改善均优于对照组,两者比较差异具有统计学意义(P<0.05)。结论 柔肝方联合恩替卡韦治疗乙肝后肝纤维化疗效肯定,能改善患者肝功能,延缓病情进展,提高患者生活质量。
Abstract:
Objective To observe the effect of RouGan decoction combined with entecavir in the treatment of patients with liver fibrosis induced by hepatitis B. Methods 60 patients with liver fibrosis induced by hepatitis B in our hospital were selected and divided into control group(30 cases) and treatment group(30 cases). The control group was treated with entecavir and the treatment group with RouGan decoction combined with entecavir, treated for 3 months. The clinical curative effect, serum liver function index and 1iver stiffness measurement, before and after the treatment were compared between the two groups. Results The total effective rate of the treatment group was 86.67%, which was higher than 63.33% of the control group. After treatment, liver function index, 1iver stiffness measurement in the treatment group were all better than those in the control group(P<0.05). Conclusion RouGan decoction combined with entecavir had a good therapeutic effect on the treatment of liver fibrosis induced by hepatitis B, it could both improve the liver function and the life quality of patients.

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备注/Memo

备注/Memo:
收稿日期: 2019 - 05- 09
* 基金项目: 国家自然科学基金青年科学基金项目(81703976)
第一作者简介: 吴惠春(1986-),男,主治中医师,研究方向:中西医结合防治慢性肝病。
更新日期/Last Update: 2020-05-06