我们的网站为什么显示成这样?

可能因为您的浏览器不支持样式,您可以更新您的浏览器到最新版本,以获取对此功能的支持,访问下面的网站,获取关于浏览器的信息:

|本期目录/Table of Contents|

基于文献数据挖掘中药复方治疗支气管扩张伴感染的用药规律*(PDF)

《云南中医学院学报》[ISSN:1000-2723/CN:53-1048/R]

期数:
2019年06期
页码:
84-89
栏目:
方药研究
出版日期:
2020-06-15

文章信息/Info

Title:
Based on Literature Data Mining, the Rule of Drug Administration of Chinese Traditional Medicine Compound for Oral Bronchodilation and Infection
文章编号:
1000-2723(2019)06-0084-06
作者:
戴冠冕1俞正秋1程 岭1蔡宛如2△
(1. 浙江中医药大学第二临床医学院,浙江 杭州 310053;2. 浙江中医药大学附属第二医院,浙江 杭州 310005)
Author(s):
DAI Guanmian1 YU Zhengqiu1 CHENG Ling1 CAI Wanru2
(1. The Second Clinical Medical College of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310053, China;2. The Second Affiliated Hospital of Zhejiang University of Traditional Chinese Medicine, Hangzhou 310005 , China)
关键词:
支气管扩张感染中药复方用药规律数据挖掘
Keywords:
bronchiectasis infection traditional Chinese medicine compound medication law data mining
分类号:
R289.1;R259
DOI:
10.19288/j.cnki.issn.1000-2723.2019.06.014
文献标识码:
A
摘要:
目的基于文献数据挖掘的方式,收集近20年文献中治疗支气管扩张伴感染的中药复方,探讨支气管扩张伴感染的中医用药规律。方法 将收集所得83个处方,运用频数分析、聚类分析、关联规则进行数据挖掘,探讨其潜在的用药规律。结果 频数分析显示共涉及药物140味,使用频次≥10次的中药有29味;聚类分析反映了清肺祛痰消痈、祛瘀止血、益气养阴的治疗方法;关联规则体现清热补虚为本病的基本方法,重视消痈排脓。结论 支气管扩张的基本病机为本虚标实,在清热祛痰排脓的同时,要兼顾益气养阴、活血化瘀。
Abstract:
Objective Based on the method of literature data mining, collect Chinese medicine prescriptions for bronchodilation and infection in the literature in the past 20 years, and explore the rules of traditional Chinese medicine for bronchodilation and infection. Methods Eighty-three prescriptions will be collected, and data analysis will be conducted using frequency analysis, cluster analysis, and association rules to explore their potential medication laws. Results Frequency analysis showed that 140 flavors of drugs were involved, and 29 flavors of Chinese medicines were used more than 10 times. The cluster analysis analysis reflected the treatment methods of clearing the lungs and removing phlegm, removing blood stasis and bleeding, and benefiting qi and nourishing yin. Tonic deficiency is the basic method of the disease, and it is important to eliminate pus. Conclusion The basic pathogenesis of bronchiectasis is based on virtual reality. While clearing heat and expelling phlegm and purging, it is necessary to take into account the benefits of nourishing qi, nourishing yin, promoting blood circulation and removing blood stasis.

参考文献/References

[1] TERPSTRA L C,BIESENBEEK S,ALTENBURG J,et al. Aetiology and disease severity are among the determinants of quality of life in bronchiectasis [J]. Clin Respir J,2019,13(8):521-529.
[2] ARA■JO D,SHTEINBERG M,ALIBERTI S,et al. The independent contribution of Pseudomonas aeruginosa infection to long-term clinical outcomes in bronchiectasis[J]. Eur Respir,2018,51(2):1701953.
[3] 徐小勇,施毅. 支气管扩张的诊断和治疗进展[J]. 中国呼吸与危重监护杂志,2017,16(2):186-190.
[4] 杨聪宾,樊茂蓉,张燕萍,等. 基于数据挖掘方法总结张燕萍教授治疗支气管扩张症用药经验[J]. 河北中医,2018,40(11):1609-1613.
[5] 陈磊,黄燕,杨爽. 从肺脾论治支气管扩张症的研究进展[J]. 内蒙古中医药,2020,39(1):157-158.
[6] 钟赣生. 中药学[M]. 北京:中国中医药出版社,2012:1-10.
[7] 南京中医药大学.中药大辞典[M]. 上海:上海科学技术出版社,2006:1-194.
[8] 李雪,马君. 陶凯教授辨治支气管扩张的经验[J]. 吉林中医药,2019,39(2):151-154.
[9] 荣毅,曲畅,李国勤,等. 李国勤教授辨治支气管扩张症经验总结[J]. 中国医药导报,2019,16(7):120-123.
[10] 闫朋朋,朱慧志,胡国俊. 胡国俊运用苇茎汤合生脉散加减治疗支气管扩张症经验[J]. 江西中医药,2017,48(6):18-20.
[11] 杨兴嫕,周奎龙,王娟,等. 史锁芳教授治疗咯血经验撷英[J]. 中国中医急症,2013,22( 9):1530-1532.
[12] 邓浩然,蔡宛如. 蔡宛如教授辛凉甘润法辨治支气管扩张的经验[J]. 陕西中医药大学学报,2016,39(5):18-20.
[13] 张艳丽,王聪,朱雷蕾,等. 黄芩苷药理作用研究进展[J]. 河南中医,2019,39(9):1450-1454.
[14] 徐红日,李雅莉,王成祥,等. 黄芩对流感病毒FM1感染所致病毒性肺炎小鼠肺中炎性细胞因子蛋白与基因表达的影响[J]. 中国中药杂志,2019,44(23):5166-5173.
[15] 邓嘉,王导新,梁爱玲,等. 黄芩苷对急性肺损伤大鼠肺泡液体清除作用的研究[J]. 重庆医科大学学报,2019,44(5):577-580.
[16] 李想,李冀. 甘草提取物活性成分药理作用研究进展[J]. 江苏中医药,2019,51(5):81-86.
[17] 陈伟,马磊,杨立山. 甘草次酸对哮喘大鼠气道重塑及肺组织Casepase-3、Bax、Bcl-2表达的影响[J]. 中药药理与临床,2016,32(4):16-19.
[18] 耿艳艳,于冰,周植星,等. 甘草次酸衍生物TY501抗肺纤维化作用及机制研究[J]. 中国药理学通报,2015,31(2):210-215.
[19] 王亚琼,喻群,张小瑾,等. 曲敬来治疗支气管扩张经验[J]. 江西中医药大学学报,2015,27(5):29-30.
[20] 张元兵,王丽华,洪广祥. 洪广祥从“治肺不远温”辨治支气管扩张[J]. 上海中医药杂志,2013,47(2):1-4.
[21] 余建玮,薛汉荣,张元兵,等. 国医大师洪广祥教授诊疗肺系疾病学术思想荟萃[J]. 中华中医药杂志,2015,30(11):3824-3829.

备注/Memo

备注/Memo:
收稿日期: 2019 -12- 09
* 基金项目: 浙江省中医药科技计划项目(2017ZKL013)
第一作者简介: 戴冠冕(1995-),男,在读硕士研究生,研究方向:中西医结合呼吸系统疾病方向。
△通信作者: 蔡宛如,E-mail:caiwanru@aliyun.com
更新日期/Last Update: 2020-06-30