Hepatic fibrosis is an abnormal repair reaction of chronic liver injury caused by a variety of reasons, which is characterized by excessive deposition of extracellular matrix and abnormal proliferation of connective tissue. Long-term chronic liver damage may develop into cirrhosis, liver failure and even liver cancer. Although hepatic fibrosis has been proved to be reversible, the mechanism of its occurrence and development is very complex. At present, no effective agent has been developed to prevent or reverse the fibrotic process directly. The unique genetic and metabolic diversity of fungi have great potential and advantages in the discovery of natural medicines. Chemical constituents of many medicinal value fungi, such as Ganoderma lucidum, Cordyceps sinensis, and Cordyceps militaris, have been reported their effects on anti-hepatic fibrosis. But there is a lack of detailed summary reports. This article reviews the research progress of medicinal value fungi in anti-hepatic fibrosis in the past decade, aiming to classify and summarize their potential mechanisms in the treatment of hepatic fibrosis, and provide reference for further treatment and prevention of hepatic fibrosis.