Lung cancer is caused by deficiency of vital Qi, loss of lung Qi, and the interaction of Qi, blood, phlegm, blood stasis, and toxin in the lung. The location of the disease is mainly in the lung, but there is an axial relationship between the liver and lung, which is based on the coexistence of Qi and blood, the system of gold and wood, and the flow opening and closing, that is, the liver and lung circulation axis. Based on the close physiological and pathological relationship between liver and lung, this paper discusses the pathogenesis and treatment of lung cancer from "hepatic pulmonary circulation axis", with a view to providing new ideas for the clinical treatment of lung cancer based on syndrome differentiation. One test case is reported.